Help & FAQ

Genecore Laboratories provides independent third-party testing for research peptides, offering HPLC purity analysis, LC-MS identity confirmation, and LAL endotoxin testing, each issued as a QR-verified digital certificate.

Suppliers and manufacturers documenting batch quality, research labs verifying incoming material, and individual researchers who want independent confirmation of what they've been sent.

Our certificates document analytical results (purity, identity, and endotoxin data) using established methods, but they are not a GMP release certificate. They're intended for research use and independent verification, not regulatory batch release.

Enter the reference code printed on the certificate into our Verify page, or scan the QR code directly. The record loads straight from our database, so you're seeing the original result, not a copy someone could have edited.

A PDF can be edited, but the reference code and QR always point back to our live database record. If the numbers on a printed certificate don't match what the lookup shows, treat the printed copy as unverified.

Place an order for the tier you need, then post your sample to our laboratory partner with the shipping instructions provided at checkout. You'll get order tracking and an email when your certificate is ready.

HPLC separates the compounds in your sample and measures purity as a percentage of the total signal. LC-MS goes further, measuring the actual molecular weight of what's present to confirm identity, not just purity.

Peptide Purity Index (PPI) looks at spectral consistency across a single peak. Sample Composition (Area%) measures what portion of the total UV-detectable signal belongs to your target peptide. They answer different questions and both matter.

Identity testing runs on a Shimadzu LCMS-8040 triple quadrupole system with ESI+ ionization, giving intact-mass confirmation across the charge-state ladder.

Purity analysis runs on a Nexera XR HPLC system with diode-array detection, using a Zorbax Extend C18 column.

Mass spectrometers respond differently to different compounds, so peak height on MS doesn't reliably represent relative quantity. HPLC's UV detector gives a much more consistent, comparable purity measurement.

This is often an adduct (the peptide bound to a sodium or potassium ion) or a dimer (two molecules briefly stuck together during ionization), not extra mass on the actual peptide. Our analysts account for this when confirming identity.

These are typically related impurities, degradation products, or synthesis by-products present in small amounts. They're reported as part of your total impurity percentage on the certificate.

A strong, clean HPLC peak only tells you the sample is chromatographically pure — not what it actually is. LC-MS is what confirms the molecular identity separately.

We use diode-array detection, which records the full UV spectrum rather than a single fixed wavelength, so this isn't typically a source of error in our results.

Purity measures how clean the sample is, not what it is. A sample can be 99% chemically pure while being 99% pure of the wrong compound. That's exactly why identity testing (LC-MS) is a separate step from purity testing (HPLC).

Different compounds can share a similar retention time under the same method. It's a useful indicator, but only mass-based identity confirmation (LC-MS) actually verifies what a compound is.

Yes. This happens when the dominant compound in the sample is not the expected peptide, even though it's chromatographically clean. It's one of the main reasons combined testing exists.

It's possible for some compounds under certain conditions. Our analysts check for this and adjust ionization parameters where appropriate before reporting a result as unconfirmed.

No. Molecular weight is a fixed property of the compound itself. HPLC method changes can affect retention time and separation, but not the mass measured by LC-MS.

Supplier certificates are typically self-reported and not independently verified. Independent testing exists precisely to check that claim against a result nobody involved in the sale generated.

No. "Not confirmed" means the evidence we obtained doesn't sufficiently support the expected identity — it isn't proof of absence. See the summary box below for exact definitions.

Not without further targeted analysis. Standard testing identifies whether your target peptide is present and how pure the sample is — it doesn't unravel every unidentified peak into a specific compound.

Your certificate leads with the headline results: HPLC purity, LC-MS identity verdict, and (if ordered) the endotoxin result — each shown with a pass/fail and the underlying number.

The chromatogram shows the raw HPLC trace: retention time on the x-axis, detector response on the y-axis. Your main peak's position and area are what purity is calculated from.

This confirms the instrument itself was performing correctly at the time of your run — resolution, tailing factor, and theoretical plates all within acceptable limits.

For multi-component blends, purity is reported per identified peak rather than as a single combined number, so you can see the composition of each component separately.